Harmonic amplification is one of the primary issues in power system networks. The objective of this study is to manage the harmonic event and its significant effects on power quality. A new control approach that uses artificial intelligence (AI) is proposed and applied to a distribution static synchronous compensator (DSTATCOM). DSTATCOM is a FACTS device that can achieve highly effective reactive power compensation to reduce and/or damp the harmonic amplification in power system networks. Simulation results are obtained using the MATLAB/Simulink package.